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KMID : 1059520230670020150
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Journal of the Korean Chemical Society
2023 Volume.67 No. 2 p.150 ~ p.155
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Anti-photoaging Constituents from Eurya emarginata Leaves
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Kim Sung-Chun
Oh So-Yeon
Hyeon Hye-Jin
Go Bo-Ram
Yoon Seon-A
Jung Yong-Hwan
Lee Nam-Ho
Ham Young-Min
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Abstract
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Eurya emarginata is an evergreen tree growing in the southern regions of Korea including Jeju Island. In this study, antioxidant and anti-photoaging effects were investigated with the extracts of E. emarginata leaves. As comparative studies with the extract and five solvent fractions, the EtOAc fraction showed the most effective DPPH and ABTS+ radical scavenging activities. The EtOAc fraction also inhibited matrix metalloproteinase-1 (MMP-1) production most effectively.
Phytochemical study on the EtOAC fraction resulted in the isolation of three compounds; eutigoside C (1), eutigoside B (2) and quercitrin (3). Among the isolates (1-3), quercitrin (3) showed excellent antioxidant activities and inhibitory properties on MMP-1 production. Based on these results, it was suggested that extracts of E. emarginata leaves could be developed as natu- ral anti-photoaging agents in cosmetic formulations.
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KEYWORD
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Eurya emarginata, Anti-oxidant, Anti-photoaging, Quercitrin
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